“True self-knowledge opens our eyes to the radical corruption of fallen man, to the radical lie which has caused his spiritual death. It therefore leads to a complete surrender to Him Who is the new root of mankind, and Who overcame death through his sufferings and death on the cross.
In Christ’s human nature our heavenly Father has revealed the fulness of meaning of all creation (Ephes 1:10), and through Him according to His Divine nature, God created all things as through the Word of his power (Heb 1:2, 3).
The primary lie obfuscating the horizon of human experience is the rebellious thought that man could do without this knowledge of God and of himself in any field of knowledge, and could find the ultimate criterion of truth in ‘autonomous’, i.e. absolutized theoretical thought.”
(Herman Dooyeweerd, A New Critique of Theoretical Thought, Vol 2, pp 563)